Research

The CureME team manage four studies, funded by the ME Association and the US government via the National Institutes of Health.

Find out more about our research publications.

Longitudinal immunological and virological study for ME/CFS biomarker discovery

Our NIH RO1 study, renewed in 2017, marked the second phase of an eight-year project that began in 2013. This renewal enabled comprehensive, regular assessments of ME cases.

With over 600 participants, multiple time points, and rigorous protocols, the study aimed to draw significant epidemiological and biomedical conclusions.

For more details, visit NIH Reporter.

Droplet digital PCR for evaluations of associations between human herpesvirus infection and ME/CFS

The study is testing for associations between herpesvirus infections and ME/CFS, and piloting a new assay that aims to detect and quantify viral loads from people with ME/CFS at monthly intervals.

The study involves 60 participants sending saliva and urine samples at regular monthly intervals over six months.

For more details, visit NIH Reporter.

Metabolic and energy requirements impacting immune function in patients with ME/CFS

This study, funded by the ME Association’s Ramsay Research Fund, is a collaboration with Dr Jo Cambridge and Fane Mensah at University College London. The two institutions are looking at T- and B-cell abnormalities in ME/CFS, and conducting extensive immunophenotyping and metabolomic analyses to further explore potential biomarkers within these cell subsets.

Find out more.

Maintaining and securing the future of the UK ME/CFS Biobank

This project is a two-year award from the ME Association Ramsay Research Fund, to provide support for the Biobank and to accelerate the release of samples to approved researchers from around the world. The award includes funding for ongoing Biobank staffing, maintenance, storage and release costs, but also includes capital for developing the Biobank’s international profile, with the aim of opening new income streams for the Biobank, reducing risk and creating a sustainable business model independent of research grant support.